WebRefractory KD is defined as the persistence or recurrence of fever (37.5°C or more of an axillary temperature) at the end of the second intravenous immunoglobulin (2 g/kg) following the initial one. Results: Subjects were enrolled out of 329 KD patients who were admitted to our 8 hospitals between January 2008 and June 2010. Web3 Department of Refractory Viral Diseases, National Center for Global Health and Medicine Research Institute, Shinjuku-ku, ... The present data indicate that a single booster dose of KD-414 induces a substantial immune response in BNT162b2-primed individuals and has a good safety profile, thereby supporting further clinical trials to identify ...
Comparison of second-line therapy in IVIg-refractory Kawasaki …
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WebFor treatment-refractory cases, immunomodulatory treatments, including corticosteroids, infliximab, anakinra, methotrexate, and cyclosporine, have been used., Cyclosporine may be beneficial for the treatment of recalcitrant KD, as recent evidence has demonstrated that the calcium-nuclear factor pathway may play a role in KD pathogenesis. WebNov 5, 2024 · When a patient with KD develops new fever within 36 h after the last dose of intravenous immunoglobulin (IVIG) infusion, IVIG resistance has to be considered. Macrophage activation syndrome is a potential complication of KD. Treatment of refractory KD includes repeated IVIG infusions with infliximab and/or corticosteroids. Keywords. … WebA refractory is a material that can stand high temperature. It is used in furnaces, kilns, incinerators and reactors. Materials to make refractory must be chemically and physically … specs 1969 mgb