WebGSH-dependent conversion of a GSH probe, Luciferin-NT, to luciferin by a glutathione S-transferase enzyme is coupled to a firefly luciferase reaction. In one configuration the reaction scheme is used to measure total glutathione. In this case a reducing agent converts all the glutathione, GSH and GSSG in a cell lysate to the reduced form, GSH. Web在本文中，我们报道了第一个能够在单个反应位点与 GSH 的硫醇基和氨基进行级联亲核取代反应的探针，并显示了 GSH 的双色识别，提高了 GSH 的选择性也是 GSH 探针的延伸。探针 Rho-DEA 基于 TICS 荧光团，分子内级联亲核取代反应与 Cys/Hcy 发生。
Rational design of reversible ... - Nature Chemistry
WebAug 24, 2024 · GSH-Activated Light-Up Near-Infrared Fluorescent Probe with High Affinity to αvβ3 Integrin for Precise Early Tumor Identification Zhenwei Yuan Zhenwei Yuan Department of Biomedical Engineering, School of Engineering, China Pharmaceutical University, 24 Tongjia Lane, Gulou District, Nanjing 210009, China More by Zhenwei … WebNov 3, 2024 · In the last few decades, growing numbers of fluorescent probes have been developed to detect intracellular GSH. However, the majority of probes for GSH were irreversible without monitoring... custom chemical supplies ltd
GSH-Glo™ Glutathione Assay - Promega
WebMar 7, 2014 · GSH, which consists of a tripeptide of glutamic acid, cysteine and glycine, is the most abundant and the representative nonprotein thiol inside the cell 3. GSH can be oxidized to its dimeric... WebJan 20, 2024 · Herein, a mitochondria-targeted near-infrared GSH probe ( JGP) was synthesized, which displayed desired properties with high specificity and sensitivity, appreciable water solubility, and rapid response time. In the presence of GSH, nearly a 13-fold fluorescence emission growth appeared at 730 nm and the solvent color changed … WebMito-RealThiol (MitoRT) Chemical Formula: C 38 H 35 BrN 3 O 3 P. Molecular Weight: 692.59. Format: Red to orange solid (Lyophilized powder in tubes) Purity: >97%, HPLC. custom champagne stopper